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Lab news:

Jun 17th, 2024. Congrats! Mingyao was awarded by the MPOWER Scholarship!


​Jun 14th, 2024. Our RFU paper is finally accepted by Cell Reports MedicineQuantifiable TCR repertoire changes in prediagnostic blood specimens among patients with high-grade ovarian cancer.

Jun 1th, 2024. Welcome our new PhD student: Tracy Wang!

May 6th, 2024. Welcome our Intern Student: Ally Mao!


Jan 9th, 2024: Our mitochondrial transfer commentary paper is published in Clinical and Translational MedicineA novel computational tool for tracking cancer energy hijacking from immune cells.

Dec 4th, 2023: Our mitochondrial paper was reported by a major Korean newspaper, Joonang Daily (central daily):  면역세포에 빨대 꽂고 벌컥…암세포 악랄 수법 드러났다. 

Nov 21st, 2023: Our mitochondrial paper is reported in NCI news & blogMolecular Burglary: Cancer Cells Hijack Energy from Immune Cells.

Oct 13th, 2023: Our mitochondrial transfer paper is highlighted on STAT news (, please click here to download the full report). STAT news is probably the most important Pharma Biotech newsletter, which is quite an impactful media and rarely reports paper on basic science. This is in fact a big deal!

Oct 9th, 2023: Our mitochondrial transfer model was reported in CHOP news!

Oct 9th, 2023: Welcome our new research-associated scientist: Hailong Hu!

Oct 6th, 2023: Dr. Bo Li hosted an amazing conference! - 8th Annual MidAtlantic Bioinformatics Conference.

Sep 24th, 2023: We had a great lab retreat at Adventure Aquarium and Fogo de Chão Brazilian Steakhouse!

Sep 5th, 2023: Our Mitochondrial Transfer paper is finally accepted by Cancer CellSystematic investigation of mitochondrial transfer between cancer cells and T cells at single-cell resolution. PDF file of the paper can be downloaded here.


Aug 24th, 2023. Welcome our new PhD student: Mingyao Pan!

Jul 28th, 2023. Welcome our new MD/PhD student: Julia Fleming!

Jun 20th, 2023. Welcome our new PhD student: Yuhao Tan!

Mar 1st, 2023: We've moved! Every end is a new beginning. After 5 years of the most rewarding time at UTSW, we are embarking on our new adventure at Children’s Hospital of Philadelphia.

Nov 8th, 2022: Our TCR convergence paper is finally accepted by elifeT cell receptor convergence is an indicator of antigen-specific T cell response in cancer immunotherapies.

Aug 24th, 2022: Our killer immunoglobulin receptors paper is finally published in BMC biologyAnalysis of KIR gene variants in The Cancer Genome Atlas and UK Biobank using KIRCLE.

Jul 19th, 2022: Our BRCA1 paper is finally accepted by BMC MedicineDissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 Mutation at single-cell resolution.

May 2nd, 2022: Our SARS-CoV-2 paper is finally published in Computational and Structural Biotechnology Journal. Computational approach for binding prediction of SARS-CoV-2 with neutralizing antibodies.

Feb 24th, 2022: Our neoantigen vaccine immunotherapy paper is finally accepted by Nature CancerConcurrent delivery of immune checkpoint blockade modulates T cell dynamics to enhance neoantigen vaccine-generated anti-tumor immunity.

Jan 26th, 2022. Welcome our new clinical research coordinator: Haley Jones!

​Jan 18th, 2022. Welcome our new research-associated scientist: Jing Hu!

Jan 1st, 2022. Welcome our new instructor: Anli Zhang!

Sep 5th, 2021: Our cancer-associated TCR paper is finally published in Bioinformatics: AutoCAT: Automated cancer-associated TCRs discovery from TCR-seq data.

Aug 4th, 2021: Our TCR clustering paper is finally published in Nature CommunicationsGIANA allows computationally-efficient TCR clustering and multi-disease repertoire classification by isometric transformation.

Mar 20th, 2020: Our cancer-associated TCR paper is finally published in Science Translational MedicineDe novo prediction of cancer-associated TCRs for non-invasive cancer detection.

Feb 3th, 2020: Our TCR paper is finally online at Clinical Cancer Research:

Aug 26th, 2019: Dr. Li is invited to present at Otto Warburg International Summer School and Research Symposium on Cell-Type Heterogeneity and Single-Cell Analysis at Shanghai, China!

Jul 15th, 2019: Welcome our new computational postdoc: Xuexin Yu!

Apr 7th, 2019: Dr. Li was invited for a interview at the SCCC for his work presented at AACR.

Feb 26th, 2019: Our BCR paper is highlighted on the ACIR weekly digest. Check it out!

Feb 13th, 2019: Our BCR paper is finally online at Nature Genetics!

Feb 08th, 2019: Hongyi is invited to give an oral presentation at AACR annual meeting 2019!

Jan 19th, 2019: Dr. Li is invited to present in a Major Symposium at AACR annual meeting 2019!

Dec 14th, 2018: Dr. Li is invited to give a talk at Chinese Biology Investigator Society biannual conference at Shenzhen, China!

Nov 20th, 2018: Our TRUST method comparison paper is published at Nature Biotechnology

Oct, 2018: Welcome our two new computational postdocs: Daria Beshnova and Hongyi Zhang!

May 2018: Welcome our new lab manager, Dr. Jianfeng Ye!

Mar 27th, 2018: Congratulations! Our Circle of Friends for Cancer Center grant proposal is funded!

Dec 22nd, 2017: Welcome Dr. Jiahui Chen to join our lab!

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