Tumor IMmune Estimation Resource

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Tcr/Bcr Repertoire Utilities for Solid Tumor/Tissue

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Tumor IMmune Estimation Resource

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Lab news:

May 2nd, 2022: Our SARS-CoV-2 paper is finally published in Computational and Structural Biotechnology Journal. Computational approach for binding prediction of SARS-CoV-2 with neutralizing antibodies.

Feb 24th, 2022: Our neoantigen vaccine immunotherapy paper is finally accepted by Nature CancerConcurrent delivery of immune checkpoint blockade modulates T cell dynamics to enhance neoantigen vaccine-generated anti-tumor immunity.

January 26th, 2022. Welcome our new clinical research coordinator: Haley Jones!

January 18th, 2022. Welcome our new computational postdoc: Jing Hu!

January 1th, 2022. Welcome our new instrucotr: Anli Zhang!

Sep 5th, 2021: Our cancer-associated TCR paper is finally published in Bioinformatics: AutoCAT: Automated cancer-associated TCRs discovery from TCR-seq data.

Aug 4th, 2021: Our TCR clustering paper is finally published in Nature CommunicationsGIANA allows computationally-efficient TCR clustering and multi-disease repertoire classification by isometric transformation.

Mar 20th, 2020: Our cancer-associated TCR paper is finally published in Science Translational MedicineDe novo prediction of cancer-associated TCRs for non-invasive cancer detection.

Feb 3th, 2020: Our TCR paper is finally online at Clinical Cancer Research:


Aug 26th, 2019: Dr. Li is invited to present at Otto Warburg International Summer School and Research Symposium on Cell-Type Heterogeneity and Single-Cell Analysis at Shanghai, China!

Jul 15th, 2019: Welcome our new computational postdoc: Xuexin Yu!

Apr 7th, 2019: Dr. Li was invited for a interview at the SCCC for his work presented at AACR.

Feb 26th, 2019: Our BCR paper is highlighted on the ACIR weekly digest. Check it out!

Feb 13th, 2019: Our BCR paper is finally online at Nature Genetics


Feb 08th, 2019: Hongyi is invited to give an oral presentation at AACR annual meeting 2019!

Jan 19th, 2019: Dr. Li is invited to present in a Major Symposium at AACR annual meeting 2019!

Dec 14th, 2018: Dr. Li is invited to give a talk at Chinese Biology Investigator Society biannual conference at Shenzhen, China!

Nov 20th, 2018: Our TRUST method comparison paper is published at Nature Biotechnology


Oct, 2018: Welcome our two new computational postdocs: Daria Beshnova and Hongyi Zhang!

May 2018: Welcome our new lab manager, Dr. Jianfeng Ye!

Mar 27th, 2018: Congratulations! Our Circle of Friends for Cancer Center grant proposal is funded!

Dec 22nd, 2017: Welcome Dr. Jiahui Chen to join our lab!