We've moved from UTSW to CHOP!
Tumor IMmune Estimation Resource
We've moved from UTSW to CHOP!
Lab news:
Mar 1st, 2023: We've moved! Every end is a new beginning. After 5 years of the most rewarding time at UTSW, we are embarking on our new adventure at Children’s Hospital of Philadelphia.
Nov 8th, 2022: Our TCR convergenece paper is finally accepted by elife: T cell receptor convergence is an indicator of antigen-specific T cell response in cancer immunotherapies.
Oct 24th, 2022: Welcome our new graduate student: Yuhao Tan!
Aug 24th, 2022: Our killer immunoglobulin receptors is finally published in BMC biology: Analysis of KIR gene variants in The Cancer Genome Atlas and UK Biobank using KIRCLE.
Jul 19th, 2022: Our BRCA1 paper is finally accepted by BMC Medicine. Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 Mutation at single-cell resolution.
May 2nd, 2022: Our SARS-CoV-2 paper is finally published in Computational and Structural Biotechnology Journal. Computational approach for binding prediction of SARS-CoV-2 with neutralizing antibodies.
Feb 24th, 2022: Our neoantigen vaccine immunotherapy paper is finally accepted by Nature Cancer: Concurrent delivery of immune checkpoint blockade modulates T cell dynamics to enhance neoantigen vaccine-generated anti-tumor immunity.
January 26th, 2022. Welcome our new clinical research coordinator: Haley Jones!
January 18th, 2022. Welcome our new computational postdoc: Jing Hu!
January 1st, 2022. Welcome our new instrucotr: Anli Zhang!
Sep 5th, 2021: Our cancer-associated TCR paper is finally published in Bioinformatics: AutoCAT: Automated cancer-associated TCRs discovery from TCR-seq data.
Aug 4th, 2021: Our TCR clustering paper is finally published in Nature Communications: GIANA allows computationally-efficient TCR clustering and multi-disease repertoire classification by isometric transformation.
Mar 20th, 2020: Our cancer-associated TCR paper is finally published in Science Translational Medicine: De novo prediction of cancer-associated TCRs for non-invasive cancer detection.
Feb 3th, 2020: Our TCR paper is finally online at Clinical Cancer Research:
https://clincancerres.aacrjournals.org/content/early/2020/01/31/1078-0432.CCR-19-3249.long
Aug 26th, 2019: Dr. Li is invited to present at Otto Warburg International Summer School and Research Symposium on Cell-Type Heterogeneity and Single-Cell Analysis at Shanghai, China!
Jul 15th, 2019: Welcome our new computational postdoc: Xuexin Yu!
Apr 7th, 2019: Dr. Li was invited for a interview at the SCCC for his work presented at AACR.
Feb 26th, 2019: Our BCR paper is highlighted on the ACIR weekly digest. Check it out!
Feb 13th, 2019: Our BCR paper is finally online at Nature Genetics:
https://www.nature.com/articles/s41588-018-0339-x!
Feb 08th, 2019: Hongyi is invited to give an oral presentation at AACR annual meeting 2019!
Jan 19th, 2019: Dr. Li is invited to present in a Major Symposium at AACR annual meeting 2019!
Dec 14th, 2018: Dr. Li is invited to give a talk at Chinese Biology Investigator Society biannual conference at Shenzhen, China!
Nov 20th, 2018: Our TRUST method comparison paper is published at Nature Biotechnology:
https://www.nature.com/articles/nbt.4294.pdf?origin=ppub
Oct, 2018: Welcome our two new computational postdocs: Daria Beshnova and Hongyi Zhang!
May 2018: Welcome our new lab manager, Dr. Jianfeng Ye!
Mar 27th, 2018: Congratulations! Our Circle of Friends for Cancer Center grant proposal is funded!
Dec 22nd, 2017: Welcome Dr. Jiahui Chen to join our lab!